SCHEMBL28346152

SCHEMBL28346152

N#C[Se]c1cc2ccccc2n(Cc2ccccc2)c1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 4/20 0.49
SMN1; SMN2 Q16637 3/20 0.46
HPGD P15428 2/20 0.46
LMNA P02545 1/20 0.46
CFTR P13569 3/20 0.45
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
GAA P10253 1/20 0.44
HTT P42858 1/20 0.44
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
ESR1 P03372 3/20 0.43
PDE9A O76083 1/20 0.42
PDE1C Q14123 1/20 0.42
P2RX4 Q99571 1/20 0.41
SRC P12931 1/20 0.41
PDE4A P27815 1/20 0.40
PDE4B Q07343 1/20 0.40
PDE4C Q08493 1/20 0.40
PDE4D Q08499 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9356192 0.79 CNR1 (0.53) CCR2SMN1; SMN2HPGDLMNACFTR
SCHEMBL28463754 0.76 CCR2 (0.49) CCR2SMN1; SMN2HPGDLMNACFTR
SCHEMBL29200758 0.75 HPGD (0.60) CCR2SMN1; SMN2HPGDLMNACFTR
SCHEMBL30783420 0.75 HPGD (0.60) CCR2SMN1; SMN2HPGDLMNACFTR
SCHEMBL13531041 0.73 CCR2 (0.55) CCR2SMN1; SMN2HPGDLMNACFTR
SCHEMBL9396355 0.73 CCR2 (0.55) CCR2SMN1; SMN2HPGDLMNACFTR
SCHEMBL8802854 0.72 CCR2 (0.54) CCR2SMN1; SMN2HPGDLMNACFTR
SCHEMBL11536101 0.71 CCR2 (0.66) CCR2SMN1; SMN2HPGDLMNAKDM4E
SCHEMBL30884510 0.71 CCR2 (0.66) CCR2SMN1; SMN2HPGDLMNAKDM4E
SCHEMBL8032176 0.70 CCR2 (0.63) CCR2SMN1; SMN2HPGDLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110563632-B Electrophilic selenocyanization reagent and preparation method and application thereof 南宁师范大学 2022-11-25 CN disclosed
CN-110563632-A electrophilic selenocyanization reagent and preparation method and application thereof 南宁师范大学 2019-12-13 CN disclosed