SCHEMBL283471

SCHEMBL283471

CCOC(=O)[N]c1cccc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
HPGD P15428 1/20 0.51
CDC25B P30305 3/20 0.50
CDC25A P30304 1/20 0.47
CDC25C P30307 1/20 0.47
KDM4E B2RXH2 3/20 0.44
KMT2A Q03164 2/20 0.44
MAPK1 P28482 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HCRTR1 O43613 1/20 0.44
TP53 P04637 1/20 0.44
MAPT P10636 1/20 0.44
ALOX15 P16050 1/20 0.44
RAB9A P51151 1/20 0.44
POLB P06746 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TSHR P16473 1/20 0.42
CYP1A2 P05177 1/20 0.41
SCN2A Q99250 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL283065 0.81 ALDH1A1 (0.44) ALDH1A1HPGDKDM4EKMT2AMAPK1
SCHEMBL4172132 0.78 SIGMAR1 (0.43) ALDH1A1HPGDCDC25BKMT2ATP53
SCHEMBL28242701 0.77 ALDH1A1 (0.48) ALDH1A1HPGDCDC25BCDC25ACDC25C
SCHEMBL7445149 0.77 SIGMAR1 (0.42) ALDH1A1HPGDKDM4EKMT2AMAPK1
SCHEMBL834358 0.75 ALDH1A1 (0.46) ALDH1A1HPGDKDM4EKMT2AMAPK1
SCHEMBL947061 0.74 SIGMAR1 (0.47) ALDH1A1HPGDCDC25BCDC25ACDC25C
SCHEMBL947060 0.74 SIGMAR1 (0.47) ALDH1A1HPGDCDC25BCDC25ACDC25C
Alpha-Naphthylisocyanate SCHEMBL9443219 0.74 ALDH1A1 (0.45) ALDH1A1HPGDCDC25BCDC25ACDC25C
SCHEMBL343533 0.73 NR4A1 (0.50) ALDH1A1HPGDCDC25BKDM4EKMT2A
SCHEMBL9451879 0.73 NPSR1 (0.42) ALDH1A1HPGDKDM4EKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111315800-B Triazine ring-containing polymer and composition comprising same 日产化学株式会社 2022-05-31 CN disclosed
CN-107849425-B Solvent-free photocurable adhesive composition 日产化学工业株式会社 2021-09-21 CN disclosed
CN-107849392-B Film-forming composition for inkjet coating 日产化学工业株式会社 2021-07-13 CN disclosed
US-20210179779-A1 TRIAZINE-RING-CONTAINING POLYMER AND COMPOSITION INCLUDING SAME NISSAN CHEMICAL CORPORATION (JP) 2021-06-17 US disclosed
CN-108602953-B Triazine ring-containing polymer and film-forming composition containing the same 日产化学工业株式会社 2021-02-05 CN disclosed
CN-111315800-A Triazine ring-containing polymer and composition comprising same 日产化学株式会社 2020-06-19 CN disclosed
US-10619073-B2 Film-forming composition for ink-jet coating NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-04-14 US disclosed
US-10604681-B2 Solvent-free light-curable adhesive composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-03-31 US disclosed
US-10266701-B2 Composition for forming protective film for transparent conductive film NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
EP-2636704-B1 FILM-FORMING COMPOSITION NISSAN CHEMICAL CORP (JP) 2019-03-27 EP disclosed
US-20130214372-A1 TRIAZINE RING-CONTAINING POLYMER AND MEMBRANE-FORMING COMPOSITION CONTAINING THE SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-08-22 US disclosed
EP-2628769-A1 FILM-FORMING COMPOSITION Nissan Chemical Industries, Ltd. (JP) 2013-08-21 EP disclosed
EP-2610280-A1 TRIAZINE RING-CONTAINING POLYMER AND MEMBRANE-FORMING COMPOSITION CONTAINING THE SAME Nissan Chemical Industries, Ltd. (JP) 2013-07-03 EP disclosed
US-20130154043-A1 FILM-FORMING COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-06-20 US disclosed
EP-2428529-A1 TRIAZINE RING-CONTAINING POLYMER AND FILM-FORMING COMPOSITION COMPRISING SAME Nissan Chemical Industries, Ltd. (JP) 2012-03-14 EP disclosed
US-20120049308-A1 TRIAZINE RING-CONTAINING POLYMER AND FILM-FORMING COMPOSITION COMPRISING SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-01 US disclosed
US-6812235-B2 2-ACYLAMINO- BETA -ALANINE DERIVATIVES AND A PHARMACEUTICALLY ACCEPTABLE SALT, USEFUL AS FIBRINOGEN RECEPTOR ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-11-02 US disclosed
US-20030018193-A1 Beta-alanine derivatives and their use as receptor anatgonists ASTELLAS PHARMA INC. (JP) 2003-01-23 US disclosed
EP-1255748-A1 BETA-ALANINE DERIVATIVES AND THEIR USE AS RECEPTOR ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-11-13 EP disclosed
WO-2001060813-A1 BETA-ALANINE DERIVATIVES AND THEIR USE AS RECEPTOR ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-08-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030018193-A1 Beta-alanine derivatives and their use as receptor anatgonists ARRB1, ADRB1, GLRB ALDH1A1 578/4885HPGD 1448/4885CDC25B 4533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.