Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLL | Q9UGP5 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17014301 | 0.79 | CA1 (0.39) | POLLKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL15617597 | 0.77 | KDM4E (0.37) | POLLKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL27490762 | 0.76 | POLL (0.41) | POLLKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29724650 | 0.74 | CYP2D6 (0.31) | KDM4EALDH1A1MAPTTP53CYP3A4 | |
| SCHEMBL8865571 | 0.74 | SLC6A2 (0.42) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL7784914 | 0.72 | ALDH1A1 (0.35) | KDM4EALDH1A1MAPTHPGDCYP3A4 | |
| SCHEMBL3823837 | 0.72 | DRD2 (0.43) | TSHRMEN1KMT2AHTR1AHTR5A | |
| Hydrochloric Acid SCHEMBL6554723 | 0.71 | HTR2C (0.33) | POLLKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL23360990 | 0.71 | KDM1A (0.31) | GAAMEN1KMT2A | |
| SCHEMBL29118170 | 0.71 | KDM1A (0.31) | GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106983751-B | Bicyclic substituted uracils and their use | 拜耳医药股份有限公司 | 2020-01-07 | — | — | CN | disclosed |