Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17014301 | 0.76 | CA1 (0.39) | HTR2CACHEHTR1AHTR1DHTR7 | |
| Hydrochloric Acid SCHEMBL6553929 | 0.73 | PTGS2 (0.31) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL6553477 | 0.71 | KDM4E (0.31) | HTR1AHTR7KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL15617597 | 0.68 | KDM4E (0.37) | HTR2CKMT2AKDM4EGAACYP3A4 | |
| SCHEMBL8865571 | 0.68 | SLC6A2 (0.42) | HTR2CHTR1AMEN1USP2KMT2A | |
| SCHEMBL16470960 | 0.66 | MEN1 (0.39) | HTR2CACHEHTR1AHTR1DHTR7 | |
| SCHEMBL16144149 | 0.65 | KDM4E (0.37) | HTR2CHTR1AHTR1DHTR7HTR5A | |
| SCHEMBL31042717 | 0.64 | KDM4E (0.39) | HTR1AMEN1KMT2AKDM4ECYP3A4 | |
| SCHEMBL3202789 | 0.63 | POLB (0.41) | HTR2CACHEKDM4EGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6356342 | 0.61 | ADRA1A (0.35) | HTR2CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773237-B1 | Olefin polymerization catalyst system | MITSUI CHEMICALS INC (JP) | 2004-02-18 | — | — | EP | disclosed |