SCHEMBL8355254

SCHEMBL8355254

COC(=O)C(Cl)C(=O)C(F)F

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.37
CA14 Q9ULX7 2/20 0.32
CA12 O43570 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28347464 0.80 SMN1; SMN2 (0.40) SMN1; SMN2CA14CA12KMT2A
SCHEMBL453120 0.79 SMN1; SMN2 (0.50) SMN1; SMN2CA14CA12KMT2A
SCHEMBL28119098 0.78 SMN1; SMN2 (0.41) SMN1; SMN2CA14CA12KMT2A
SCHEMBL2327769 0.77 ALDH1A1 (0.39) KMT2A
SCHEMBL197339 0.75 SMN1; SMN2 (0.40) SMN1; SMN2CA14CA12KMT2A
SCHEMBL11411272 0.74
SCHEMBL28156637 0.73 SMN1; SMN2 (0.48) SMN1; SMN2CA14CA12KMT2A
SCHEMBL237982 0.73
SCHEMBL5076701 0.73 SMN1; SMN2 (0.41) SMN1; SMN2CA14CA12KMT2A
SCHEMBL4110912 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240410055-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2024-12-12 US disclosed
CN-118076767-A Method and formulation for producing an optical metal oxide layer 默克专利有限公司 2024-05-24 CN disclosed
WO-2023057401-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2023-04-13 WO disclosed
US-5877119-A HERBICIDE ROHM AND HAAS COMPANY (US) 1999-03-02 US disclosed
US-5843867-A Substituted pyridine compounds ROHM AND HAAS COMPANY (US) 1998-12-01 US disclosed
US-5824625-A HERBICIDES, HETEROCYCLIC GROUP(S) ATTACHED TO PYRIDINE RING ROHM AND HAAS COMPANY 1998-10-20 US disclosed
US-5643854-A HERBICIDES ROHM AND HAAS COMPANY (US) 1997-07-01 US disclosed
US-5512536-A HERBICIDE ROHN AND HAAS COMPANY (US) 1996-04-30 US disclosed
US-5424274-A Herbicides ROHM AND HAAS COMPANY (US) 1995-06-13 US disclosed
US-5391540-A Herbicides ROHM AND HAAS COMPANY (US) 1995-02-21 US disclosed
US-5219824-A Preemergence, postemergence herbicides MONSANTO COMPANY (US) 1993-06-15 US disclosed
EP-0278944-B1 SUBSTITUTED 2,6-SUBSTITUTED PYRIDINE COMPOUNDS Monsanto Company (US) 1992-09-30 EP disclosed
WO-1992014711-A1 SUBSTITUTED PYRIDINE COMPOUNDS MONSANTO COMPANY (US) 1992-09-03 WO disclosed
US-5129943-A Herbicides MONSANTO COMPANY (US) 1992-07-14 US disclosed
US-5125956-A Preemergence herbicides MONSANTO COMPANY (US) 1992-06-30 US disclosed
US-5100461-A Substituted 2,6-substituted pyridine compounds having herbicidal activity MONSANTO COMPANY (US) 1992-03-31 US disclosed
US-4988384-A HERBICIDES, PLANT GROWTH REGULATORS, ANTIGROWTH AGENTS MONSANTO COMPANY (US) 1991-01-29 US disclosed
US-4826532-A HERBICIDES MONSANTO COMPANY (US) 1989-05-02 US disclosed
EP-0278945-A2 Substituted 2,6-substituted pyridine compounds Monsanto Company (US) 1988-08-17 EP disclosed
EP-0278944-A1 Substituted 2,6-substituted pyridine compounds Monsanto Company (US) 1988-08-17 EP disclosed