Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22023439 | 1.00 | CCKBR (0.42) | CCKBRPPARGCCR1CHRM2MAPT | |
| SCHEMBL20601122 | 0.90 | NPSR1 (0.38) | CCR1CHRM2MAPTTSHRCASP3 | |
| SCHEMBL20601121 | 0.90 | NPSR1 (0.38) | CCR1CHRM2MAPTTSHRCASP3 | |
| SCHEMBL20600893 | 0.88 | PLD2 (0.38) | CCR1CHRM2MAPTTSHRCASP3 | |
| SCHEMBL20600894 | 0.88 | PLD2 (0.38) | CCR1CHRM2MAPTTSHRCASP3 | |
| SCHEMBL20600981 | 0.85 | CCKBR (0.43) | CCKBRCCR1MEN1KMT2ASLC6A12 | |
| SCHEMBL20600979 | 0.85 | CCKBR (0.43) | CCKBRCCR1MEN1KMT2ASLC6A12 | |
| SCHEMBL20615629 | 0.85 | GPR119 (0.47) | MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL28347947 | 0.85 | GPR119 (0.47) | MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL20601115 | 0.83 | PLD2 (0.41) | CCR1CHRM2MAPTTSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110709391-A | Modulators of indoleamine2, 3-dioxygenase | 葛兰素史克知识产权开发有限公司 | 2020-01-17 | — | — | CN | disclosed |