SCHEMBL28347756

SCHEMBL28347756

Brc1cccs1.c1cc2sncc2cn1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.34
CYP2E1 P05181 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2B6 P20813 1/20 0.34
TRPM5 Q9NZQ8 1/20 0.33
POLB P06746 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL88831 0.81
SCHEMBL30051093 0.81
Azetidine SCHEMBL20336251 0.71 ROCK1 (0.36) CYP2A6CYP3A4
Pyridine SCHEMBL28219020 0.71 TSHR (0.45) CYP2A6CYP2E1CYP3A4CYP2C9CYP2B6
SCHEMBL4767521 0.69
SCHEMBL1254977 0.69 FBP1 (0.41) POLBKDM4EHSD17B10
SCHEMBL22395 0.69
Pyrimidine SCHEMBL28088660 0.68 CYP2A6 (0.41) CYP2A6CYP2E1CYP3A4CYP2C9CYP2B6
Pyridine SCHEMBL28928518 0.67 TDO2 (0.37) TRPM5KDM4EHSD17B10
SCHEMBL18247606 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108329460-B Photodynamic bactericidal polymer and preparation method and application thereof 山西大学 2020-01-03 CN disclosed