SCHEMBL28348175

SCHEMBL28348175

CC(C)c1cc(I)cc(C(C)C)c1C(N)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.54
GABRB1 P18505 3/20 0.54
GABRB2 P47870 1/20 0.54
FABP3 P05413 2/20 0.44
FABP4 P15090 2/20 0.44
ALDH1A1 P00352 1/20 0.37
EGFR P00533 1/20 0.33
POLB P06746 2/20 0.32
GAA P10253 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
RET P07949 1/20 0.31
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
SLC9A1 P19634 2/20 0.31
SLC9A2 Q9UBY0 1/20 0.31
TTR P02766 1/20 0.31
FABP5 Q01469 1/20 0.31
AURKA O14965 1/20 0.30
AURKB Q96GD4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8017724 0.81 FABP4 (0.67) GABRA1GABRB2FABP3FABP4ALDH1A1
SCHEMBL1275261 0.74 GABRA1 (0.50) GABRA1GABRB1GABRB2FABP3FABP4
SCHEMBL28014363 0.71 FABP3 (0.58) GABRA1GABRB2FABP3FABP4ALDH1A1
SCHEMBL7123500 0.70 GABRA1 (0.58) GABRA1GABRB1GABRB2POLBGAA
SCHEMBL1163939 0.70 GABRA1 (1.00) GABRA1GABRB1GABRB2ALDH1A1GAA
SCHEMBL9356500 0.70 TTR (0.43) POLBTTR
SCHEMBL27899937 0.70 PARP10 (0.50) FABP3FABP4
Hydrochloric Acid SCHEMBL27899942 0.69 PARP10 (0.49)
Water SCHEMBL28207330 0.69 PARP10 (0.49) FABP3FABP4
SCHEMBL20915178 0.68 GAA (0.50) GABRA1GABRB1GABRB2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110563961-B Preparation and application of tridentate isonitrile and organic metal microporous framework materials MOMFs 山东师范大学 2022-04-15 CN claimed
CN-110563961-B Preparation and application of tridentate isonitrile and organic metal microporous framework materials MOMFs 山东师范大学 2022-04-15 CN disclosed
CN-110563961-A Preparation and application of tridentate isonitrile and organic metal microporous framework materials MOMFs 山东师范大学 2019-12-13 CN disclosed