Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 17/20 | 0.70 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14902624 | 1.00 | FPR2 (0.70) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL28352113 | 0.86 | FPR2 (0.63) | FPR2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14902575 | 0.86 | FPR2 (0.63) | FPR2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6315910 | 0.85 | CYP3A4 (0.54) | FPR2MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7342352 | 0.84 | FPR2 (0.52) | FPR2MAPTNPSR1 | |
| SCHEMBL7338444 | 0.84 | FPR2 (0.52) | FPR2MAPTNPSR1 | |
| SCHEMBL5421613 | 0.84 | MAPT (0.60) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL20671518 | 0.84 | CA12 (0.57) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL5421619 | 0.84 | MAPT (0.60) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL14948969 | 0.84 | TP53 (0.52) | FPR2MEN1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518742-B | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators | 阿勒根公司 | 2020-01-21 | — | — | CN | disclosed |