Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DDX3X | O00571 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20522279 | 0.95 | RAB9A (0.58) | RAB9AKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL28348666 | 0.91 | HDAC1 (0.55) | RAB9AKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL28352566 | 0.89 | BLM (0.46) | RAB9AKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL28348731 | 0.88 | RAB9A (0.52) | RAB9AKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL20522361 | 0.83 | KDM4E (0.49) | RAB9AKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL20522282 | 0.83 | RAB9A (0.57) | RAB9AKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL28352303 | 0.83 | RAB9A (0.50) | RAB9AKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL28352563 | 0.80 | HDAC1 (0.54) | KDM4EMAPTKMT2AMEN1POLB | |
| SCHEMBL28348979 | 0.80 | CSNK2A2 (0.47) | RAB9AKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL28348729 | 0.79 | HDAC1 (0.57) | RAB9AKDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024352-A | Novel inhibitors | 维沃里翁治疗股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-110719910-B | Novel inhibitors | 维沃里翁治疗股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-110719910-A | Novel inhibitors | 前体生物药物股份公司 | 2020-01-21 | — | — | CN | disclosed |