Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.62 |
| ▸ | CTSK | P43235 | 14/20 | 0.59 |
| ▸ | CTSL | P07711 | 6/20 | 0.59 |
| ▸ | CTSS | P25774 | 4/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.58 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | REN | P00797 | 1/20 | 0.56 |
| ▸ | PREP | P48147 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14493034 | 0.98 | ACE (0.64) | ACECTSKCTSLCTSSACE2 | |
| SCHEMBL20484750 | 0.98 | ACE (0.64) | ACECTSKCTSLCTSSACE2 | |
| SCHEMBL7392156 | 0.98 | ACE (0.64) | ACECTSKCTSLCTSSACE2 | |
| Boric Acid SCHEMBL28346456 | 0.95 | ACE (0.61) | ACECTSKCTSLCTSSACE2 | |
| SCHEMBL20173777 | 0.92 | ACE (0.65) | ACECTSKCTSLCTSSACE2 | |
| SCHEMBL8334160 | 0.91 | CTSK (0.60) | ACECTSKCTSLCTSSCTSB | |
| SCHEMBL2499034 | 0.90 | ALDH1A1 (0.61) | ACECTSKCTSLCTSSCTSB | |
| SCHEMBL6243546 | 0.88 | ACE (0.66) | ACEACE2PREPLMNA | |
| SCHEMBL6244068 | 0.88 | ACE (0.66) | ACEACE2PREPLMNA | |
| SCHEMBL9574253 | 0.87 | ACE (0.76) | ACEACE2REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929340-B | Proline boric acid compound and preparation method and application thereof | 北京大学 | 2019-12-13 | — | — | CN | claimed |
| CN-108929340-B | Proline boric acid compound and preparation method and application thereof | 北京大学 | 2019-12-13 | — | — | CN | disclosed |