Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MMP8 | P22894 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28349566 | 0.80 | ALDH1A1 (0.43) | KMT2AMEN1MAPTL3MBTL1TNKS | |
| SCHEMBL14664065 | 0.78 | XDH (0.58) | KMT2AMEN1MAPTIDO1MMP2 | |
| SCHEMBL28352766 | 0.77 | ERBB2 (0.40) | KMT2AMEN1TNKSIDO1 | |
| SCHEMBL9678766 | 0.72 | MAPT (0.54) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL28352544 | 0.69 | ALDH1A1 (0.46) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL28352680 | 0.69 | ADORA2A (0.42) | KMT2AMEN1MAPTL3MBTL1IDO1 | |
| SCHEMBL20380220 | 0.68 | HPGD (0.68) | KMT2AMEN1MAPTL3MBTL1TNKS | |
| SCHEMBL10481615 | 0.68 | ALDH1A1 (0.51) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL28348877 | 0.67 | ALDH1A1 (0.43) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31001160 | 0.65 | ALDH1A1 (0.46) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590760-B | 2, 1-benzisoxazole derivative and synthetic method and application thereof | 武汉工程大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-110590760-A | 2, 1-benzisoxazole derivative and synthetic method and application thereof | 武汉工程大学 | 2019-12-20 | — | — | CN | disclosed |