Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28349566 | 0.71 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28352766 | 0.69 | ERBB2 (0.40) | MEN1KMT2AERBB2ALOX15 | |
| SCHEMBL8959133 | 0.68 | ALDH1A1 (0.81) | ALDH1A1MAPTMEN1KMT2AGFER | |
| SCHEMBL9955974 | 0.67 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2AGFER | |
| SCHEMBL28348874 | 0.67 | KMT2A (0.47) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9214142 | 0.64 | NR4A2 (0.47) | ALDH1A1MAPTMEN1KMT2AGFER | |
| SCHEMBL28346770 | 0.62 | ESR1 (0.59) | ALDH1A1MAPTMEN1KMT2AGFER | |
| SCHEMBL12330213 | 0.61 | ALDH1A1 (0.63) | ALDH1A1MAPTMEN1KMT2AGFER | |
| SCHEMBL11469513 | 0.61 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2AGFER | |
| SCHEMBL11632404 | 0.61 | ALDH1A1 (0.72) | ALDH1A1MAPTMEN1KMT2AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590760-B | 2, 1-benzisoxazole derivative and synthetic method and application thereof | 武汉工程大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-110590760-A | 2, 1-benzisoxazole derivative and synthetic method and application thereof | 武汉工程大学 | 2019-12-20 | — | — | CN | disclosed |