Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9955960 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPTMEN1GFER | |
| SCHEMBL9214142 | 0.79 | NR4A2 (0.47) | ALDH1A1KMT2AMAPTMEN1GFER | |
| SCHEMBL1839676 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KMT2ASMN1; SMN2HPGDLMNA | |
| SCHEMBL6819286 | 0.69 | KDM4E (0.48) | ALDH1A1MAPTSMN1; SMN2HPGDTSHR | |
| SCHEMBL9953480 | 0.67 | LMNA (0.47) | ALDH1A1KMT2AMAPTMEN1GFER | |
| SCHEMBL9955574 | 0.67 | MEN1 (0.41) | ALDH1A1KMT2AMAPTMEN1GFER | |
| SCHEMBL17423119 | 0.65 | POLB (0.55) | ALDH1A1KMT2ANR4A2POLBSOS2 | |
| SCHEMBL2708419 | 0.65 | ENPP2 (0.54) | ALDH1A1KMT2AMAPTMEN1GFER | |
| SCHEMBL6989194 | 0.65 | FAAH (0.51) | ALDH1A1KMT2AMAPTMEN1GFER | |
| SCHEMBL8959133 | 0.64 | ALDH1A1 (0.81) | ALDH1A1KMT2AMAPTMEN1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085857-A1 | 3,8-DIAZA-BICYCLO[4.2.0]OCT-3-YL AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-28 | — | — | WO | disclosed |