Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30531884 | 0.87 | POLB (0.41) | RORCPSIP1POLBMEN1KMT2A | |
| SCHEMBL28352546 | 0.82 | PSIP1 (0.39) | RORCPSIP1MEN1KMT2ALMNA | |
| SCHEMBL28349448 | 0.80 | PSIP1 (0.42) | RORCPSIP1MEN1KMT2AMAPT | |
| SCHEMBL28352399 | 0.76 | PSIP1 (0.53) | RORCPSIP1 | |
| SCHEMBL2828915 | 0.67 | S1PR3 (0.48) | RORCIRAK4POLBMAPK1 | |
| SCHEMBL28349856 | 0.67 | PSIP1 (0.44) | RORCPSIP1 | |
| SCHEMBL28236908 | 0.66 | RORC (0.53) | RORC | |
| SCHEMBL30531883 | 0.66 | RORC (0.49) | RORCIRAK4MEN1KMT2ALMNA | |
| SCHEMBL3871603 | 0.66 | IRAK4 (0.55) | IRAK4POLBLMNA | |
| SCHEMBL30474513 | 0.65 | PSIP1 (0.42) | RORCPSIP1POLBLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024319-A | Amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-110724075-B | Amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-110724075-A | Amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2020-01-24 | — | — | CN | disclosed |