Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 5/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.33 |
| ▸ | S100A10 | P60903 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30531884 | 0.82 | POLB (0.41) | PSIP1L3MBTL1MEN1KMT2ARORC | |
| SCHEMBL7844303 | 0.82 | MAPK8 (0.40) | ALDH1A1PARP1 | |
| SCHEMBL28352399 | 0.81 | PSIP1 (0.53) | PSIP1KIF11GAAALDH1A1RORC | |
| SCHEMBL28352546 | 0.80 | PSIP1 (0.39) | PSIP1KIF11MAPTMEN1KMT2A | |
| SCHEMBL28349092 | 0.80 | RORC (0.41) | PSIP1MAPTMEN1KMT2ARORC | |
| SCHEMBL28349856 | 0.71 | PSIP1 (0.44) | PSIP1KIF11GAARORC | |
| SCHEMBL28236908 | 0.70 | RORC (0.53) | RORC | |
| SCHEMBL30474513 | 0.69 | PSIP1 (0.42) | PSIP1KIF11GAAALDH1A1RORC | |
| Ammonia Solution, Strong SCHEMBL29200040 | 0.69 | PSIP1 (0.42) | PSIP1KIF11GAAALDH1A1RORC | |
| SCHEMBL28128227 | 0.68 | LMNA (0.44) | GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024319-A | Amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-110724075-B | Amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-110724075-A | Amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2020-01-24 | — | — | CN | disclosed |