Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12214127 | 0.83 | KDM4E (0.42) | KDM4EMEN1KMT2AGAAMAPT | |
| SCHEMBL15304521 | 0.81 | KDM4E (0.41) | KDM4EMEN1KMT2AGAAMAPT | |
| SCHEMBL1004574 | 0.81 | KDM4E (0.58) | KDM4EMEN1KMT2AGAAMAPT | |
| SCHEMBL4686503 | 0.79 | PSMB5 (0.40) | KDM4EMEN1KMT2AGAAMAPT | |
| SCHEMBL9267218 | 0.79 | KDM4E (0.40) | KDM4EMEN1KMT2AGAAMAPT | |
| SCHEMBL436968 | 0.79 | PLA2G2A (0.41) | KDM4EMEN1KMT2AGAAMAPT | |
| SCHEMBL1258869 | 0.79 | SMN1; SMN2 (0.36) | ALDH1A1SLC22A12SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL3104254 | 0.79 | ALDH1A1 (0.41) | KDM4EMEN1KMT2AGAAMAPT | |
| SCHEMBL9715052 | 0.78 | GABRA1 (0.42) | KDM4EMEN1KMT2AGAAMAPT | |
| SCHEMBL7690997 | 0.77 | ERCC5 (0.48) | KDM4EMEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142988-A1 | METHOD OF PRODUCING 1-HEXENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| WO-2011016581-A1 | METHOD OF PRODUCING 1-HEXENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142988-A1 | METHOD OF PRODUCING 1-HEXENE | HRH1, HK1, HMOX1 | KDM4E 2710/4885MEN1 250/4885KMT2A 2250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.