Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LONP1 | P36776 | 6/20 | 0.48 |
| ▸ | PSMB11 | A5LHX3 | 5/20 | 0.48 |
| ▸ | PSMA7 | O14818 | 5/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.48 |
| ▸ | PSMA1 | P25786 | 5/20 | 0.48 |
| ▸ | PSMA2 | P25787 | 5/20 | 0.48 |
| ▸ | PSMA3 | P25788 | 5/20 | 0.48 |
| ▸ | PSMA4 | P25789 | 5/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 5/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 5/20 | 0.48 |
| ▸ | PSMA5 | P28066 | 5/20 | 0.48 |
| ▸ | PSMB4 | P28070 | 5/20 | 0.48 |
| ▸ | PSMB6 | P28072 | 5/20 | 0.48 |
| ▸ | PSMB10 | P40306 | 5/20 | 0.48 |
| ▸ | PSMB3 | P49720 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3932153 | 1.00 | PSMB5 (0.61) | PSMB5HPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL28147568 | 0.89 | PSMB5 (0.59) | PSMB5HPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL28349240 | 0.87 | PSMB5 (0.60) | PSMB5HPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL28349239 | 0.87 | PSMB5 (0.60) | PSMB5HPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL5939842 | 0.84 | L3MBTL1 (0.59) | MEN1ALDH1A1KMT2AGPR132GAA | |
| SCHEMBL5939834 | 0.84 | L3MBTL1 (0.59) | MEN1ALDH1A1KMT2AGPR132GAA | |
| SCHEMBL28758530 | 0.80 | ITGB1 (0.47) | GPR132NPR3MMEITGB1ITGA4 | |
| SCHEMBL18274606 | 0.79 | GAA (0.51) | PSMB5MEN1ALDH1A1KMT2ALONP1 | |
| SCHEMBL20543718 | 0.79 | TPH1 (0.57) | MMEITGB1ITGA4 | |
| SCHEMBL20543715 | 0.79 | TPH1 (0.57) | MMEITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009004350-A1 | METHODS FOR PREPARING BORTEZOMIB AND INTERMEDIATES USED IN ITS MANUFACTURE | PLIVA HRVATSKA D.O.O. (HR) | 2009-01-08 | — | — | WO | disclosed |