SCHEMBL28349484

SCHEMBL28349484

Cc1cccc2c1C(=O)C(C)(C)C2(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CD44 P16070 1/20 0.37
PDK2 Q15119 4/20 0.36
GRIA1 P42261 2/20 0.33
CACNG8 Q8WXS5 2/20 0.33
HTR7 P34969 1/20 0.33
HTR2B P41595 1/20 0.33
PDE7A Q13946 1/20 0.33
CNR1 P21554 1/20 0.33
HTT P42858 1/20 0.33
GPR35 Q9HC97 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
DAO P14920 1/20 0.33
DPP4 P27487 1/20 0.33
MYC P01106 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12319822 0.69 PDK2 (0.60) CD44PDK2CYP1A2CYP2A6
SCHEMBL12718616 0.69 PSMB1 (0.40) CA1CA2CA7CA9CD44
SCHEMBL20029441 0.68 CA1 (0.39) CA1CA2CA7CA9CD44
SCHEMBL20000877 0.68 PDK2 (0.32) CD44PDK2
SCHEMBL1987048 0.68 CA1 (0.46) CA1CA2CA7CA9GRIA1
SCHEMBL6256987 0.68 PGR (0.44) CA1CA2CA7CA9CD44
SCHEMBL20886845 0.68 DAO (0.39) CA1CA2CA7CA9CD44
SCHEMBL28527151 0.67 HTR2A (0.35) PDK2PDK4
SCHEMBL12276528 0.67 PDK2 (0.31) CD44PDK2
SCHEMBL28613659 0.67 HTR7 (0.49) CA1CA2CA7CA9CD44

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110632207-B Method for identifying mold based on volatile gas components and evolution trend thereof 南京财经大学 2022-04-29 CN disclosed
CN-110632207-A Method for identifying mold based on volatile gas components and evolution trend thereof 南京财经大学 2019-12-31 CN disclosed