Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24383281 | 0.91 | ALDH1A1 (0.44) | MEN1KMT2AHDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL20149858 | 0.89 | ALDH1A1 (0.46) | MEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL28349581 | 0.87 | HDAC6 (0.44) | HDAC6CYP3A4CYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL30910298 | 0.87 | HDAC6 (0.44) | HDAC6CYP3A4CYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL25598334 | 0.86 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL23373452 | 0.84 | ASAH1 (0.51) | MEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL24383374 | 0.84 | KMT2A (0.43) | MEN1KMT2AHDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL8842993 | 0.83 | MMP2 (0.46) | MEN1KMT2AHDAC6CYP3A4ALDH1A1 | |
| SCHEMBL20149856 | 0.82 | ALDH1A1 (0.45) | MEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL19463708 | 0.80 | HDAC6 (0.43) | HDAC6CYP3A4CYP2D6ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110741087-A | Targeted compositions | 阿布特斯生物制药公司 | 2020-01-31 | — | — | CN | disclosed |