Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL22265217 | 0.98 | LMNA (0.35) | LMNAMEN1KMT2AHTR2AHRH1 | |
| SCHEMBL1503494 | 0.98 | LMNA (0.37) | LMNAMEN1KMT2AHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL1880314 | 0.97 | LMNA (0.36) | LMNAMEN1KMT2AHTR2AHRH1 | |
| SCHEMBL2832101 | 0.92 | LMNA (0.34) | LMNAMEN1KMT2AHTR2AHRH1 | |
| SCHEMBL5297040 | 0.90 | LMNA (0.32) | LMNA | |
| SCHEMBL5303167 | 0.87 | LMNA (0.30) | LMNAPOLB | |
| SCHEMBL5302234 | 0.87 | HPGD (0.32) | LMNATSHRPOLB | |
| Trifluoromethanesulfonic Acid SCHEMBL2830948 | 0.84 | KCNH2 (0.34) | KMT2A | |
| Bromide SCHEMBL22265218 | 0.82 | HKDC1 (0.33) | — | |
| Bromide SCHEMBL9661595 | 0.81 | CYP17A1 (0.39) | TSHRPOLBCYP19A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048327-A1 | Highly-Neutralized Golf Ball Compositions | ACUSHNET COMPANY | 2010-02-25 | — | — | US | disclosed |