Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL22265217 | 0.98 | LMNA (0.35) | LMNACYP19A1TSHRMEN1KMT2A | |
| SCHEMBL1503494 | 0.98 | LMNA (0.37) | LMNACYP19A1TSHRMEN1KMT2A | |
| Bromide SCHEMBL2835014 | 0.97 | LMNA (0.36) | LMNACYP19A1TSHRMEN1KMT2A | |
| SCHEMBL2832101 | 0.92 | LMNA (0.34) | LMNAMEN1KMT2AHTR2AHRH1 | |
| SCHEMBL5297040 | 0.90 | LMNA (0.32) | LMNA | |
| SCHEMBL5302234 | 0.87 | HPGD (0.32) | LMNATSHRPOLB | |
| SCHEMBL5303167 | 0.87 | LMNA (0.30) | LMNAPOLB | |
| Trifluoromethanesulfonic Acid SCHEMBL2830948 | 0.84 | KCNH2 (0.34) | KMT2A | |
| Bromide SCHEMBL22265218 | 0.82 | HKDC1 (0.33) | — | |
| SCHEMBL28332725 | 0.80 | GABBR2 (0.39) | MEN1KMT2APOLBKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8083945-B2 | Fluid storage and purification method and system | MATHESON TRI-GAS, INC. (US) | 2011-12-27 | — | — | US | claimed |
| US-20100223208-A1 | FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | MATHESON TRI-GAS, INC. (US) | 2010-09-02 | — | — | US | claimed |
| US-8083945-B2 | Fluid storage and purification method and system | MATHESON TRI-GAS, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-7955416-B2 | Polymerized polymeric fluid storage and purification method and system | MATHESON TRI-GAS, INC. (US) | 2011-06-07 | — | — | US | disclosed |
| US-7938968-B2 | storing and dispensing a fluid includes providing a vessel configured for selective dispensing of the fluid therefrom. The vessel contains an ionic liquid therein. The fluid is contacted with the ionic liquid for take-up of the fluid by the ionic liquid. | MATHESON TRI GAS (US) | 2011-05-10 | — | — | US | disclosed |
| US-7896954-B2 | storing and dispensing a fluid includes providing a vessel configured for selective dispensing of the fluid therefrom; The fluid is contacted with the ionic liquid for take-up of the fluid by the ionic liquid | MATHESON TRI-GAS, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-20100223208-A1 | FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | MATHESON TRI-GAS, INC. (US) | 2010-09-02 | — | — | US | disclosed |
| US-20100140175-A1 | POLYMERIZED POLYMERIC FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | MATHESON TRI-GAS (US) | 2010-06-10 | — | — | US | disclosed |
| US-7670490-B2 | Fluid storage and purification method and system | MATHESON TRI-GAS, INC. (US) | 2010-03-02 | — | — | US | disclosed |
| US-20100048327-A1 | Highly-Neutralized Golf Ball Compositions | ACUSHNET COMPANY | 2010-02-25 | — | — | US | disclosed |
| US-20090320771-A1 | IONIC LIQUID MEDIUMS FOR HOLDING SOLID PHASE PROCESS GAS PRECURSORS | MATHESON TRI-GAS (US) | 2009-12-31 | — | — | US | disclosed |
| US-7585415-B2 | Fluid storage and purification method and system | MATHESON TRI-GAS (US) | 2009-09-08 | — | — | US | disclosed |
| US-20080211118-A1 | FLUID STORAGE AND DISPENSING APPARATUS | MATHESON TRI-GAS, INC. (US) | 2008-09-04 | — | — | US | disclosed |
| US-20080210633-A1 | FLUID STORAGE AND PURIFICATION METHOD | MATHESON TRI-GAS, INC. (US) | 2008-09-04 | — | — | US | disclosed |
| EP-1877153-A1 | FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | Matheson Tri-Gas (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006110450-A9 | FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | MATHESON TRI GAS (US) | 2006-11-23 | — | — | WO | disclosed |
| WO-2006110450-A1 | FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | MATHESON TRI-GAS (US) | 2006-10-19 | — | — | WO | disclosed |
| US-20060226072-A1 | Fluid storage and purification method and system | MATHESON TRI-GAS | 2006-10-12 | — | — | US | disclosed |
| US-20060226074-A1 | Fluid storage and purification method and system | MATHESON TRI-GAS | 2006-10-12 | — | — | US | disclosed |
| US-20060226073-A1 | Fluid storage and purification method and system | MATHESON TRI-GAS | 2006-10-12 | — | — | US | disclosed |