Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.31 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.31 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9920688 | 0.71 | ADORA2A (0.43) | KDM4EALDH1A1MAPTHPGDPPARG | |
| SCHEMBL17981684 | 0.62 | FDPS (0.33) | KDM4EALDH1A1TDP1P2RY2 | |
| SCHEMBL30093042 | 0.62 | ALDH1A1 (0.35) | KDM4EALDH1A1MAPTHPGDPPARG | |
| SCHEMBL30960690 | 0.61 | KDM4E (0.39) | KDM4EALDH1A1MAPTHPGDPPARG | |
| SCHEMBL29861959 | 0.61 | ADORA2A (0.42) | KDM4EALDH1A1MAPTHPGDPPARG | |
| SCHEMBL30637303 | 0.61 | KDM4E (0.41) | KDM4EALDH1A1MAPTHPGDPPARG | |
| SCHEMBL996451 | 0.61 | ADORA2A (0.42) | KDM4EALDH1A1MAPTHPGDPPARG | |
| SCHEMBL15102970 | 0.60 | FDPS (0.35) | TDP1 | |
| SCHEMBL4103871 | 0.60 | SRC (0.50) | TDP1 | |
| SCHEMBL28418285 | 0.59 | SRC (0.41) | KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110573518-A | Substituted bicyclic pyrimidinyl compounds, compositions and uses thereof | 尤拉·S·赞特里佐斯 | 2019-12-13 | — | — | CN | disclosed |