Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 6/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 4/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28356899 | 0.81 | DAO (0.45) | DAOTAAR1MAPTOPRL1 | |
| SCHEMBL29259245 | 0.75 | AR (0.43) | ARMAPT | |
| SCHEMBL29259242 | 0.75 | DHODH (0.43) | — | |
| SCHEMBL28352950 | 0.75 | AR (0.43) | ARMAPT | |
| SCHEMBL28356859 | 0.74 | NQO2 (0.39) | ARMAPT | |
| SCHEMBL29259243 | 0.73 | TOP2A (0.37) | ARMAPT | |
| SCHEMBL28958657 | 0.71 | PARP1 (0.42) | MAPT | |
| SCHEMBL21008875 | 0.70 | TRPV4 (0.39) | ARPDE3BPDE3A | |
| SCHEMBL28882601 | 0.70 | AR (0.43) | AR | |
| SCHEMBL22439122 | 0.68 | DAO (0.38) | DAOMRGPRX4TAAR1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-110770211-A | α unsaturated amide compound | 协和麒麟株式会社 | 2020-02-07 | — | — | CN | disclosed |