Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 10/20 | 0.35 |
| ▸ | PDE2A | O00408 | 3/20 | 0.34 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28352950 | 0.74 | AR (0.43) | ARMAPTSLC6A4 | |
| SCHEMBL29259245 | 0.74 | AR (0.43) | ARMAPTCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL29259242 | 0.74 | DHODH (0.43) | — | |
| SCHEMBL28356859 | 0.73 | NQO2 (0.39) | ARMAPT | |
| SCHEMBL28352964 | 0.73 | DAO (0.43) | ARMAPT | |
| SCHEMBL28958657 | 0.73 | PARP1 (0.42) | MAPTCYP2D6 | |
| SCHEMBL21008875 | 0.69 | TRPV4 (0.39) | ARPGR | |
| SCHEMBL28882601 | 0.69 | AR (0.43) | ARSLC6A4 | |
| SCHEMBL22438917 | 0.69 | CETP (0.33) | TOP2ATOP2BARPDE2AIGFBP3 | |
| SCHEMBL20554025 | 0.68 | ELANE (0.44) | TOP2ATOP2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |