SCHEMBL28353000

SCHEMBL28353000

O=S(=O)(c1cccc2cc3ccccc3cc12)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 2/20 0.40
GAA P10253 2/20 0.40
CA2 P00918 2/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
CCR2 P41597 1/20 0.36
RORA P35398 1/20 0.35
RORC P51449 1/20 0.35
NR1H2 P55055 1/20 0.35
NR1H4 Q96RI1 1/20 0.35
CES1 P23141 1/20 0.34
TTR P02766 1/20 0.34
FABP4 P15090 1/20 0.34
CCNA2 P20248 1/20 0.34
CDK2 P24941 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3241709 0.83 CA1 (0.57) ALDH1A1KDM4ECA2CA1CA9
SCHEMBL3768625 0.79 HTR6 (0.46) ALDH1A1KDM4EGAACA2CA1
SCHEMBL660554 0.77 ALDH1A1 (0.44) ALDH1A1KDM4EGAACA2CA1
Anthracene SCHEMBL27538789 0.77 TTR (0.50) ALDH1A1KDM4EGAACA2CA1
SCHEMBL155232 0.77 TTR (0.50) ALDH1A1KDM4EGAACA2CA1
SCHEMBL29623319 0.77 TTR (0.50) ALDH1A1KDM4EGAACA2CA1
SCHEMBL6929900 0.76 CA2 (0.44) ALDH1A1GAACA2CA1CA9
SCHEMBL7983819 0.76 POLB (0.39) ALDH1A1KDM4EGAACCR2MEN1
SCHEMBL1394934 0.76 TTR (0.48) ALDH1A1KDM4EGAACA2CA1
SCHEMBL725590 0.76 ALDH1A1 (0.43) ALDH1A1KDM4EGAACA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108495833-B Novel compound and semiconductor material containing same DIC株式会社 2021-04-16 CN disclosed
CN-110627602-A Organic photoelectric semiconductor material and synthesis method and application thereof 天津大学 2019-12-31 CN disclosed