Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150443 | 0.82 | ALDH1A1 (0.46) | LMNATSHRALDH1A1HSD17B10KDM4E | |
| SCHEMBL28409026 | 0.80 | KMT2A (0.61) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL31561829 | 0.78 | KMT2A (0.55) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL43644 | 0.78 | KMT2A (0.67) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL4444645 | 0.78 | KMT2A (0.67) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL29408467 | 0.78 | KMT2A (0.67) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL28147702 | 0.78 | TSPO (0.47) | TSHRALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL29271836 | 0.76 | KMT2A (0.65) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL13041521 | 0.76 | KMT2A (0.56) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL30492227 | 0.76 | KMT2A (0.64) | KMT2ALMNATSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749214-B | Compound containing 1, 3-benzoxazole difluoromethylene indolone and preparation method thereof | 上海大学 | 2020-01-17 | — | — | CN | disclosed |