Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.39 |
| ▸ | GPR39 | O43194 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17869122 | 0.85 | F2RL3 (0.45) | ALDH1A1TSHRCREBBPSMN1; SMN2MAPT | |
| SCHEMBL4236522 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL17869288 | 0.76 | EGLN1 (0.47) | CREBBPHSD17B10 | |
| SCHEMBL19434598 | 0.71 | LMNA (0.42) | KAT6AKAT5KAT8HPGDMEN1 | |
| SCHEMBL5108545 | 0.70 | ALDH1A1 (0.40) | MAPK1ALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL25122887 | 0.70 | EGLN1 (0.53) | SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL21248208 | 0.69 | SMN1; SMN2 (0.42) | MAPK1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16415457 | 0.68 | TSHR (0.48) | MAPK1ALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL20660562 | 0.68 | SMN1; SMN2 (0.46) | MAPK1ALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL29220666 | 0.68 | CRHBP (0.43) | MAPK1ALDH1A1TSHRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406451-B | Pyrrolopyrimidines and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors | 福马治疗股份有限公司 | 2019-12-17 | — | — | CN | disclosed |