Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28349542 | 0.82 | NPC1 (0.40) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL16021678 | 0.81 | KIF11 (0.46) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL13658487 | 0.80 | KIF11 (0.47) | KIF11SLC6A1SLC6A11KCNH2 | |
| SCHEMBL28353348 | 0.78 | SLC6A11 (0.40) | RAB9ASMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL23571163 | 0.77 | EHMT2 (0.50) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL15471570 | 0.76 | KIF11 (0.43) | MAPTKIF11SLC6A1SLC6A11KCNH2 | |
| SCHEMBL28882285 | 0.75 | KIF11 (0.40) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL16197752 | 0.75 | KIF11 (0.50) | TP53KIF11SLC6A1SLC6A11KCNH2 | |
| SCHEMBL8327519 | 0.75 | KIF11 (0.42) | TP53KIF11SLC6A1SLC6A11KCNH2 | |
| SCHEMBL12582832 | 0.75 | KIF11 (0.42) | TP53KIF11SLC6A1SLC6A11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617314-B1 | OLIGONUCLEOTIDE DERIVATIVE OR SALT THEREOF | KYOWA KIRIN CO LTD (JP) | 2023-02-15 | — | — | EP | disclosed |
| CN-110603330-A | Oligonucleotide derivative or salt thereof | 协和麒麟株式会社 | 2019-12-20 | — | — | CN | disclosed |