SCHEMBL28354553

SCHEMBL28354553

Cc1ccc(C(O[PH](=O)O)c2ccccc2)cc1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 4/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
IDO1 P14902 2/20 0.33
TDO2 P48775 2/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 1/20 0.33
RECQL P46063 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
TP53 P04637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
IDO2 Q6ZQW0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28354551 0.87 MEN1 (0.36) MEN1KMT2ACES2CES1TDP1
SCHEMBL767298 0.83 ESR1 (0.40) KMT2ACES2CES1IDO1TDO2
Butane SCHEMBL4824910 0.78 POLB (0.42) MEN1KMT2AALDH1A1CYP1A2HTT
SCHEMBL27990971 0.73 ESR1 (0.39) MEN1KMT2ACES2CES1TDP1
SCHEMBL3762861 0.69 MAPT (0.33) MEN1KMT2ATDP1ALDH1A1CYP3A4
SCHEMBL2819632 0.69 HCAR2 (0.44) KMT2AALDH1A1LMNA
SCHEMBL10006852 0.69 MEN1 (0.44) MEN1KMT2ACES2CES1CYP2C9
SCHEMBL767297 0.67 IDO1 (0.39) CYP1A2IDO1TDO2HTTIDO2
SCHEMBL17615187 0.67 MEN1 (0.33) MEN1KMT2AIDO1TDO2IDO2
Butane SCHEMBL8718621 0.67 L3MBTL1 (0.47) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105867081-B Electrophotographic photoreceptor and image forming apparatus 柯尼卡美能达株式会社 2020-02-14 CN disclosed