Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL4824910 | 0.90 | POLB (0.42) | CYP2D6LMNAMAPK1KMT2APOLB | |
| SCHEMBL28354553 | 0.83 | MEN1 (0.37) | IDO1TDO2LMNAKMT2ACES2 | |
| SCHEMBL767297 | 0.81 | IDO1 (0.39) | ESR1ESR2IDO1TDO2SRC | |
| SCHEMBL6910195 | 0.80 | ESR1 (0.35) | ESR1ESR2IDO1TDO2SRD5A2 | |
| SCHEMBL5745420 | 0.80 | LMNA (0.41) | SRCCYP2D6LMNAMAPK1KMT2A | |
| SCHEMBL64260 | 0.80 | LMNA (0.41) | SRCCYP2D6LMNAMAPK1KMT2A | |
| SCHEMBL2795973 | 0.78 | TDP1 (0.38) | ESR1ESR2SRCCYP2D6LMNA | |
| SCHEMBL17061038 | 0.78 | DPP4 (0.41) | SRCCYP2D6LMNAMAPK1 | |
| SCHEMBL2819632 | 0.78 | HCAR2 (0.44) | SRCCYP2D6LMNAKMT2APOLB | |
| SCHEMBL8173543 | 0.78 | SRC (0.37) | SRCCYP2D6LMNAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367775-B | High-molecular weight atactic copolymerization based on bis-phenol（Phosphonate ester carbonic ester） | FRX 聚合物股份有限公司 | 2018-04-13 | — | — | CN | claimed |
| CN-105367775-A | High molecular weight, random, bisphenol based copoly(phosphonate carbonate)s | FRX POLYMERS INC | 2016-03-02 | — | — | CN | claimed |
| CN-103282405-B | Bisphenol-based high molecular weight random copolymerization (phosphonate carbonate) | FRX POLYMERS, INC. (US) | 2016-01-20 | — | — | CN | claimed |
| US-8648163-B2 | High molecular weight, random, bisphenol based copoly(phosphonate carbonate)s | FRX POLYMERS, INC. (US) | 2014-02-11 | — | — | US | claimed |
| CN-103282405-A | Bisphenol-based high molecular weight random copolymerization (phosphonate carbonate) | FRX POLYMERS INC | 2013-09-04 | — | — | CN | claimed |
| EP-2616496-A2 | HIGH MOLECULAR WEIGHT, RANDOM, BISPHENOL BASED COPOLY(PHOSPHONATE CARBONATE)S | FRX Polymers, Inc. (US) | 2013-07-24 | — | — | EP | claimed |
| US-20130158147-A1 | HIGH MOLECULAR WEIGHT, RANDOM, BISPHENOL BASED COPOLY(PHOSPHONATE CARBONATE)S | BAYER MATERIAL SCIENCE AG (DE) | 2013-06-20 | — | — | US | claimed |
| US-8389664-B2 | High molecular weight, random, bisphenol based copoly(phosphonate carbonate)s | FRX POLYMERS, INC. (US) | 2013-03-05 | — | — | US | claimed |
| WO-2012037500-A2 | HIGH MOLECULAR WEIGHT, RANDOM, BISPHENOL BASED COPOLY(PHOSPHONATE CARBONATE)S | FRX POLYMERS, INC. (US) | 2012-03-22 | — | — | WO | claimed |
| US-20120068115-A1 | HIGH MOLECULAR WEIGHT, RANDOM, BISPHENOL BASED COPOLY(PHOSPHONATE CARBONATE)S | BAYER MATERIAL SCIENCE AG (DE) | 2012-03-22 | — | — | US | claimed |
| CN-110804121-B | Low-smoke low-toxicity high-flame-retardancy polymethacrylimide foam | 湖南博翔新材料有限公司 | 2021-11-30 | — | — | CN | disclosed |
| US-10717931-B2 | Curing of epoxy resins with phosphonate oligomers | FRX POLYMERS, INC. (US) | 2020-07-21 | — | — | US | disclosed |
| CN-111433198-A | Urea derivatives as inhibitors of ASK1 | 合帕吉恩治疗公司 | 2020-07-17 | — | — | CN | disclosed |
| CN-110804121-A | Low-smoke low-toxicity high-flame-retardancy polymethacrylimide foam | 湖南博翔新材料有限公司 | 2020-02-18 | — | — | CN | disclosed |
| EP-3565822-A1 | CURING OF EPOXY RESINS WITH PHOSPHONATE OLIGOMERS | FRX Polymers, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |
| US-4892955-A | HYDROGENATION OF A DICARBOXYLIC ACID, DICARBOXYLIC ACID ANHYDRIDE AND/OR DICARBOXYLIC ACID ESTER; RUTHENIUM CATALYST | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0114703-B1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACIDS AND/OR ESTERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-10-15 | — | — | EP | disclosed |
| EP-0124160-B1 | A PROCESS FOR THE PREPARATION OF CARBOXYLIC ACIDS AND/OR ESTERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-09-17 | — | — | EP | disclosed |
| EP-0124160-A1 | A process for the preparation of carboxylic acids and/or esters | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-11-07 | — | — | EP | disclosed |
| EP-0114703-A1 | Process for the preparation of carboxylic acids and/or esters | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717931-B2 | Curing of epoxy resins with phosphonate oligomers | PFAS, PHOSPHO1, PPA1 | ESR1 378/4885ESR2 885/4885IDO1 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.