SCHEMBL2819632

SCHEMBL2819632

CC(O[PH](=O)O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.44
FFAR1 O14842 1/20 0.42
KMT2A Q03164 1/20 0.39
POLB P06746 1/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2C P18825 1/20 0.38
LMNA P02545 1/20 0.38
HIF1A Q16665 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALOX5 P09917 2/20 0.37
CYP2D6 P10635 1/20 0.37
SRC P12931 1/20 0.37
ALDH1A1 P00352 1/20 0.36
TRPA1 O75762 1/20 0.36
PTGS1 P23219 1/20 0.36
RORC P51449 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL247698 0.93 FFAR1 (0.42) HCAR2FFAR1KMT2APOLBLMNA
SCHEMBL2819629 0.83 HCAR2 (0.43) HCAR2FFAR1KMT2AADRA2AADRA2C
SCHEMBL28980059 0.83 HCAR2 (0.43) HCAR2FFAR1KMT2AADRA2AADRA2C
SCHEMBL28980086 0.80 ADRB2 (0.42) KMT2APOLBHIF1ACYP2D6ALDH1A1
SCHEMBL27850458 0.80 HTT (0.34) KMT2ALMNAHIF1AKDM4EALOX5
SCHEMBL767298 0.78 ESR1 (0.40) KMT2APOLBLMNACYP2D6SRC
SCHEMBL5745420 0.77 LMNA (0.41) KMT2APOLBLMNACYP2D6SRC
SCHEMBL64260 0.77 LMNA (0.41) KMT2APOLBLMNACYP2D6SRC
SCHEMBL4737454 0.76 KMT2A (0.41) KMT2APOLBLMNACYP2D6SRC
Biphenyl SCHEMBL27587289 0.75 PDCD1 (0.47) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115724887-A Process for the synthesis of chiral alpha-phosphorus compounds 武汉大学 2023-03-03 CN disclosed
US-8604233-B2 Lubricant composition, magnetic recording medium, and novel polyether compound FUJIFILM CORPORATION (JP) 2013-12-10 US disclosed
US-7812171-B2 Black pigment, black pigment dispersion and black resin composition comprising the same FUJIFILM CORPORATION (JP) 2010-10-12 US disclosed
US-20100247971-A1 LUBRICANT COMPOSITION, MAGNETIC RECORDING MEDIUM, AND NOVEL POLYETHER COMPOUND FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
US-20080262237-A1 BLACK PIGMENT, BLACK PIGMENT DISPERSION AND BLACK RESIN COMPOSITION COMPRISING THE SAME FUJIFILM CORPORATION (JP) 2008-10-23 US disclosed
CN-1230889-A NAALADase compositions and methods for treating glutamate abnormalities and for producing neuronal activity in animals GUILFORD PHARM INC (US) 1999-10-06 CN disclosed
EP-0318392-B1 N-(VINBLASTINOYL-23)DERIVATIVES OF 1-AMINO METHYLPHOSPHONIC ACIDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ADIR ET COMPAGNIE (FR) 1992-04-15 EP disclosed
EP-0318392-A1 N-(vinblastinoyl-23)derivatives of 1-amino methylphosphonic acids, processes for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1989-05-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100247971-A1 LUBRICANT COMPOSITION, MAGNETIC RECORDING MEDIUM, AND NOVEL POLYETHER COMPOUND MUC1, NEFM, CA13 HCAR2 1054/4885FFAR1 1322/4885KMT2A 1894/4885
US-20080262237-A1 BLACK PIGMENT, BLACK PIGMENT DISPERSION AND BLACK RESIN COMPOSITION COMPRISING THE SAME DYNLL1, HNRNPL, AOX1 HCAR2 4628/4885FFAR1 4308/4885KMT2A 2975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.