Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 5/20 | 0.32 |
| ▸ | HTR7 | P34969 | 6/20 | 0.31 |
| ▸ | HTR1A | P08908 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 2/20 | 0.31 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831981 | 0.88 | SLC6A2 (0.34) | SLC6A2SLC6A3SLC6A4CASP3CASP7 | |
| SCHEMBL2835767 | 0.77 | CASP3 (0.32) | CASP3HTR7CASP7 | |
| SCHEMBL2833663 | 0.73 | HTR7 (0.33) | SLC6A2SLC6A3SLC6A4CASP3HTR7 | |
| SCHEMBL2836548 | 0.72 | CA12 (0.38) | CASP3HTR7HRH4CASP7CA12 | |
| SCHEMBL3406648 | 0.70 | HCRTR1 (0.36) | CASP3CASP7BDKRB1 | |
| SCHEMBL2832782 | 0.69 | CA12 (0.39) | CASP3HTR7CASP7CA12CA1 | |
| SCHEMBL3408124 | 0.69 | BDKRB1 (0.41) | BDKRB1 | |
| SCHEMBL3408252 | 0.68 | HTR7 (0.47) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL3412223 | 0.68 | BDKRB1 (0.36) | HTR7HTR1ADRD2HTR1DHTR2B | |
| SCHEMBL3410519 | 0.68 | BDKRB1 (0.38) | CASP3CASP7BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100173889-A1 | Substituted Pyrimidine and Triazine Compounds | GRUENENTHAL GMBH (DE) | 2010-07-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173889-A1 | Substituted Pyrimidine and Triazine Compounds | ADORA2B, CCNB1, TYMS | SLC6A2 2863/4885SLC6A3 2272/4885SLC6A4 2062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.