Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.66 |
| ▸ | MAOA | P21397 | 13/20 | 0.66 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.59 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751126 | 0.81 | MAOB (0.78) | MAOBMAOAPDE3BPDE3ACREBBP | |
| SCHEMBL2236580 | 0.80 | MAOB (1.00) | MAOBMAOACREBBP | |
| SCHEMBL6031474 | 0.77 | EGFR (0.50) | PDE3BPDE3A | |
| SCHEMBL3875255 | 0.77 | MAOA (0.68) | MAOBMAOA | |
| Hydrochloric Acid SCHEMBL3902331 | 0.76 | MAOA (0.66) | MAOBMAOA | |
| SCHEMBL6421129 | 0.74 | MAOA (0.64) | MAOBMAOA | |
| SCHEMBL27648074 | 0.74 | MAOB (0.71) | MAOBMAOA | |
| SCHEMBL20520341 | 0.73 | MAOA (0.79) | MAOBMAOACREBBP | |
| SCHEMBL6225615 | 0.73 | MAOB (0.63) | MAOBMAOA | |
| SCHEMBL9728150 | 0.73 | MAOB (1.00) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749045-B | D-amino acid oxidase inhibitor and preparation method and application thereof | 上海交通大学 | 2020-02-14 | — | — | CN | disclosed |