Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SLC8B1 | Q6J4K2 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.43 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177430 | 0.82 | MAPT (0.50) | MAPTTSHRTP53CYP1A2CYP2C9 | |
| SCHEMBL13981274 | 0.78 | TSHR (0.52) | MAPTTSHRTP53CYP1A2CYP2C9 | |
| SCHEMBL10371606 | 0.76 | MAPT (0.44) | MAPTTSHRTP53CYP1A2CYP2C9 | |
| SCHEMBL5435436 | 0.76 | MAPT (0.56) | MAPTTSHRTP53CYP1A2CYP2C9 | |
| SCHEMBL28470317 | 0.74 | KMT2A (0.41) | MAPTTSHRTP53CYP1A2CYP2C9 | |
| SCHEMBL8117192 | 0.73 | MAPT (0.60) | MAPTTSHRTP53CYP1A2CYP2C9 | |
| SCHEMBL31444453 | 0.73 | ALDH1A1 (0.60) | TSHRTP53RECQLSMN1; SMN2KDM4E | |
| SCHEMBL31071906 | 0.72 | TP53 (1.00) | MAPTTSHRTP53CYP1A2CYP2C9 | |
| SCHEMBL869274 | 0.72 | TP53 (1.00) | MAPTTSHRTP53CYP1A2CYP2C9 | |
| SCHEMBL10929981 | 0.70 | MAPT (0.77) | MAPTTSHRTP53CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110790714-A | Preparation process of lorazepam impurity D | 华中药业股份有限公司 | 2020-02-14 | — | — | CN | disclosed |