SCHEMBL2835608

SCHEMBL2835608

COc1ccc2c(c1)OCC2C(=O)C1COc2cc(OC)ccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.48
USP2 O75604 2/20 0.48
MAPT P10636 3/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ABCB1 P08183 2/20 0.47
MTNR1A P48039 4/20 0.46
CYP19A1 P11511 1/20 0.45
DRD2 P14416 1/20 0.44
DRD3 P35462 1/20 0.44
LTB4R Q15722 2/20 0.43
LTB4R2 Q9NPC1 2/20 0.43
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TP53 P04637 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31432485 0.88 MTNR1A (0.47) CYP3A4USP2MAPTMAPK1TDP1
SCHEMBL25318575 0.79 CYP3A4 (0.54) CYP3A4USP2MAPTMAPK1TDP1
SCHEMBL206776 0.78 MTNR1A (0.49) CYP3A4USP2MAPTMAPK1TDP1
SCHEMBL1570633 0.78 PTGDR2 (0.50)
SCHEMBL205181 0.77 LTB4R (0.50) CYP3A4USP2MAPTMAPK1TDP1
SCHEMBL11000702 0.77 HTR1A (0.43) CYP3A4USP2MAPTMAPK1TDP1
SCHEMBL206775 0.77 PPARD (0.69) FFAR1PPARGPPARD
SCHEMBL24766430 0.76 MTNR1A (0.50) MAPTMTNR1ACYP19A1DRD2DRD3
SCHEMBL2691621 0.76 PPARD (0.54) MTNR1AFFAR1PPARGPPARD
SCHEMBL1478719 0.76 USP2 (0.44) CYP3A4USP2MAPTMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192898-B2 Composition for fluorine-containing volume holographic data recording material and fluorine-containing volume holographic data recording media made of same DAIKIN INDUSTRIES, LTD. (JP) 2012-06-05 US disclosed
US-20100112460-A1 COMPOSITION FOR FLUORINE-CONTAINING VOLUME HOLOGRAPHIC DATA RECORDING MATERIAL AND FLUORINE-CONTAINING VOLUME HOLOGRAPHIC DATA RECORDING MEDIA MADE OF SAME UMEDA CENTER BUILDING (JP) 2010-05-06 US disclosed