SCHEMBL28356239

SCHEMBL28356239

Nc1cccc(B(O)O)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 4/20 0.44
NOS3 P29474 3/20 0.44
ASIC3 Q9UHC3 1/20 0.40
NCF1 P14598 2/20 0.38
PLAU P00749 1/20 0.38
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ENPP2 Q13822 1/20 0.37
GRM4 Q14833 1/20 0.35
XIAP P98170 1/20 0.34
BIRC2 Q13490 1/20 0.34
BACE1 P56817 4/20 0.33
NOS1 P29475 2/20 0.32
PI4KA P42356 1/20 0.32
PI4K2B Q8TCG2 1/20 0.32
PI4K2A Q9BTU6 1/20 0.32
PI4KB Q9UBF8 1/20 0.32
PLG P00747 1/20 0.31
F12 P00748 1/20 0.31
F11 P03951 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16908606 0.88 NOS3 (0.41) NOS2NOS3ASIC3NCF1PLAU
SCHEMBL20067383 0.82 ENPP2 (0.36) ALDH1A1KDM4EENPP2
SCHEMBL31139482 0.75 CCR1 (0.40) ALDH1A1KDM4EENPP2
SCHEMBL29956196 0.73 ENPP2 (0.34) ALDH1A1ENPP2
SCHEMBL64599 0.73
SCHEMBL29955389 0.71 CCR1 (0.48) NOS2NOS3ALDH1A1KDM4EGRM4
SCHEMBL313923 0.71 HTR7 (0.35) ALDH1A1
SCHEMBL2265930 0.71 TSHR (0.41) ALDH1A1ENPP2
SCHEMBL31138329 0.71 MAPT (0.32)
SCHEMBL1718324 0.71 MAPT (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115873250-B Black polyimide containing pyrrolopyrrole diketone structure and preparation method and application thereof 湖南工业大学 2024-04-05 CN claimed
CN-115873250-B Black polyimide containing pyrrolopyrrole diketone structure and preparation method and application thereof 湖南工业大学 2024-04-05 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-107849045-B purinyl-N-hydroxypyrimidine carboxamide derivative and preparation method and application thereof 贵州百灵企业集团制药股份有限公司 2019-12-24 CN disclosed