Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CTSB | P07858 | 3/20 | 0.51 |
| ▸ | CTSH | P09668 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 4/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3759121 | 0.84 | CASP3 (0.37) | CTSKCTSLCTSBCTSHMEN1 | |
| SCHEMBL6039781 | 0.81 | HSD17B10 (0.40) | CTSKCTSLCTSBCTSHMEN1 | |
| SCHEMBL3760487 | 0.79 | HSD17B10 (0.39) | CTSKCTSLCTSBCTSHMEN1 | |
| SCHEMBL6856059 | 0.77 | CTSL (0.56) | CTSKCTSLCTSBCTSHUCHL1 | |
| SCHEMBL30749079 | 0.77 | CTSL (0.56) | CTSKCTSLCTSBCTSHUCHL1 | |
| SCHEMBL2261903 | 0.77 | CASP3 (0.43) | CASP3HPGDFKBP1AEPHX1HSD17B10 | |
| SCHEMBL29894062 | 0.77 | HPGD (0.41) | CASP3HPGDFKBP1AEPHX1HSD17B10 | |
| SCHEMBL7538169 | 0.77 | HPGD (0.41) | CASP3HPGDFKBP1AEPHX1HSD17B10 | |
| SCHEMBL17595518 | 0.77 | HPGD (0.41) | CASP3HPGDFKBP1AEPHX1HSD17B10 | |
| SCHEMBL17595517 | 0.77 | HPGD (0.41) | CASP3HPGDFKBP1AEPHX1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945382-B | Substituted piperidines that increase p53 activity and uses thereof | 默沙东公司 | 2020-02-07 | — | — | CN | disclosed |