SCHEMBL30749079

SCHEMBL30749079

COC(=O)[C@@H]1CCCN1C#N

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CTSL P07711 2/20 0.56
CTSB P07858 2/20 0.56
CTSH P09668 2/20 0.56
CTSK P43235 2/20 0.56
POLB P06746 1/20 0.44
PEPD P12955 2/20 0.43
UCHL1 P09936 10/20 0.41
XPNPEP1 Q9NQW7 1/20 0.40
FKBP1A P62942 1/20 0.39
USP30 Q70CQ3 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6856059 1.00 CTSL (0.56) CTSLCTSBCTSHCTSKPOLB
SCHEMBL6856402 0.89 CTSK (0.52) CTSLCTSBCTSHCTSKPOLB
SCHEMBL555492 0.84 POLB (0.45) CTSLCTSBCTSHCTSKPOLB
SCHEMBL20308345 0.82 POLB (0.44) CTSLCTSBCTSHCTSKPOLB
SCHEMBL6884054 0.77 CTSL (0.47) CTSLCTSBCTSHCTSKUCHL1
SCHEMBL707281 0.77 CTSL (0.47) CTSLCTSBCTSHCTSKUCHL1
SCHEMBL707280 0.77 CTSL (0.47) CTSLCTSBCTSHCTSKUCHL1
SCHEMBL28356288 0.77 CTSK (0.51) CTSLCTSBCTSHCTSKUCHL1
SCHEMBL2224182 0.75 LTA4H (0.43) CTSLCTSBCTSHCTSKPOLB
SCHEMBL2224603 0.75 LTA4H (0.43) CTSLCTSBCTSHCTSKPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT CTSL 627/4885CTSB 320/4885CTSH 1366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.