Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12555393 | 0.79 | ALDH1A1 (0.49) | HSD17B10MYCWDR5MAPTALDH1A1 | |
| SCHEMBL28357048 | 0.78 | TGFBR1 (0.57) | HSD17B10MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL8236684 | 0.75 | MEN1 (0.48) | HSD17B10MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL1747883 | 0.74 | ALDH1A1 (0.63) | HSD17B10MAPTALDH1A1NPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL17673846 | 0.73 | ALDH1A1 (0.61) | HSD17B10MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL10668923 | 0.72 | NOS1 (0.62) | HSD17B10MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL28127303 | 0.71 | MAPT (0.53) | HSD17B10MYCWDR5MAPTALDH1A1 | |
| SCHEMBL28357067 | 0.70 | MAPT (0.51) | HSD17B10MYCWDR5MAPTALDH1A1 | |
| SCHEMBL18550724 | 0.69 | NPY5R (0.47) | HSD17B10MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL3514395 | 0.69 | NPC1 (0.54) | HSD17B10MAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341789-B | Synthesis method of 4, 5-disubstituted-2-aminothiazole compound | 浙江大学 | 2020-02-21 | — | — | CN | disclosed |