Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 8/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28361032 | 0.88 | DYRK1A (0.47) | ALDH1A1HSD17B10TGFBR1AKT1PIK3CA | |
| SCHEMBL28357096 | 0.75 | VRK1 (0.33) | TGFBR1VRK1 | |
| SCHEMBL4054554 | 0.75 | ALDH1A1 (0.50) | RIPK2ALOX5APFEN1ALDH1A1HSD17B10 | |
| SCHEMBL29388659 | 0.75 | ALDH1A1 (0.50) | RIPK2ALOX5APFEN1ALDH1A1HSD17B10 | |
| SCHEMBL28048502 | 0.75 | ALDH1A1 (0.54) | PIK3CDRIPK2ALOX5APFEN1ALDH1A1 | |
| SCHEMBL3311489 | 0.74 | DYRK1A (0.46) | PIK3CDRIPK2ALOX5APFEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27261649 | 0.72 | ALDH1A1 (0.47) | RIPK2ALOX5APFEN1ALDH1A1HSD17B10 | |
| SCHEMBL1854129 | 0.72 | CYP2A6 (0.45) | PIK3CDRIPK2ALOX5APFEN1ALDH1A1 | |
| SCHEMBL21625029 | 0.71 | RIPK2 (0.45) | PIK3CDRIPK2ALOX5APFEN1ALDH1A1 | |
| SCHEMBL1851318 | 0.70 | TRPV3 (0.44) | PIK3CDRIPK2ALOX5APFEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | claimed |
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | disclosed |