Sugi Predict

Sugi Predict / Compounds / SCHEMBL4054554

SCHEMBL4054554

SCHEMBL4054554

Fc1ccc2scnc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.50
▸ HSD17B10 Q99714 1/20 0.50
▸ NPC1 O15118 4/20 0.43
▸ RAB9A P51151 4/20 0.43
▸ RIPK2 O43353 4/20 0.43
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ HSD11B1 P28845 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ HKDC1 Q2TB90 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ AXL P30530 1/20 0.37
▸ GFER P55789 1/20 0.37
▸ TRPM5 Q9NZQ8 1/20 0.37
▸ NAMPT P43490 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37
▸ DYRK1A Q13627 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29388659 1.00 ALDH1A1 (0.50) ALDH1A1HSD17B10NPC1RAB9ARIPK2
Hydrochloric Acid SCHEMBL27261649 0.96 ALDH1A1 (0.47) ALDH1A1HSD17B10NPC1RAB9ARIPK2
Bromoethane SCHEMBL27399289 0.89 ALDH1A1 (0.41) ALDH1A1HSD17B10NPC1RAB9ARIPK2
SCHEMBL1671036 0.83 NPC1 (0.54) ALDH1A1HSD17B10NPC1RAB9AMEN1
SCHEMBL9843851 0.81 ALDH1A1 (0.42) ALDH1A1HSD17B10RIPK2KDM4ESMN1; SMN2
Ammonia Solution, Strong SCHEMBL28327531 0.81 NPC1 (0.53) ALDH1A1HSD17B10NPC1RAB9AMEN1
SCHEMBL1850866 0.80 NFE2L2 (0.44) ALDH1A1HSD17B10NPC1RAB9ARIPK2
SCHEMBL1850868 0.80 NFE2L2 (0.44) ALDH1A1HSD17B10NPC1RAB9ARIPK2
Benzene SCHEMBL27557967 0.79 NPC1 (0.53) ALDH1A1HSD17B10NPC1RAB9AMEN1
Hydrazine SCHEMBL27557475 0.79 NPC1 (0.51) ALDH1A1HSD17B10NPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115667209-A Compounds for the treatment of SARS 普渡研究基金会 2023-01-31 — — CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 — — US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 — — US claimed
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 — — EP claimed
US-4889796-A CONTAINING BENZOXAZOLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1989-12-26 — — US claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 — — US claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 — — EP claimed
US-3977882-A CARBOCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 — — US claimed
JP-5241265-A — — None — — JP disclosed
US-12545671-B2 Compound having biological activity such as antiviral activity NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE (JP) 2026-02-10 — — US disclosed
US-20250320201-A1 COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS AGIOS PHARMACEUTICALS INC (US) 2025-10-16 — — US disclosed
US-20250171438-A1 COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS AGIOS PHARMACEUTICALS, INC. 2025-05-29 — — US disclosed
US-20250092040-A1 AKT1 MODULATORS ALTEROME THERAPEUTICS, INC. 2025-03-20 — — US disclosed
US-20240246951-A1 COMPOUND HAVING BIOLOGICAL ACTIVITY SUCH AS ANTIVIRAL ACTIVITY NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE (JP) 2024-07-25 — — US disclosed
US-3977883-A Spectrally sensitized silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 — — US disclosed
US-3976492-A CYANINE DYE SENSITIZERS FUJI PHOTO FILM CO., LTD. (JA) 1976-08-24 — — US disclosed
US-3967967-A CYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-07-06 — — US disclosed
US-3955996-A Method for spectrally sensitizing photographic light-sensitive emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-05-11 — — US disclosed
US-3953215-A X-RAY FILM FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 — — US disclosed
US-3951666-A CYANINE AND MEROCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545671-B2 Compound having biological activity such as antiviral activity SARS1, ACE2, ACE ALDH1A1 2867/4885HSD17B10 2602/4885NPC1 59/4885
US-20240246951-A1 COMPOUND HAVING BIOLOGICAL ACTIVITY SUCH AS ANTIVIRAL ACTIVITY RNASE1, ZC3HAV1, ACE ALDH1A1 1459/4885HSD17B10 2409/4885NPC1 647/4885
US-20250320201-A1 COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS PAH, KDM8, PHF8 ALDH1A1 865/4885HSD17B10 1477/4885NPC1 3526/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR ALDH1A1 4757/4885HSD17B10 4363/4885NPC1 917/4885
US-20250092040-A1 AKT1 MODULATORS AKT1S1, AKT1, AKT2 ALDH1A1 4692/4885HSD17B10 1835/4885NPC1 1743/4885
US-20250171438-A1 COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS PAH, KDM8, PHF8 ALDH1A1 865/4885HSD17B10 1477/4885NPC1 3526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.