Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD11 | O00231 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 11/20 | 0.44 |
| ▸ | QPCTL | Q9NXS2 | 6/20 | 0.44 |
| ▸ | PRKCI | P41743 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AOC2 | O75106 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360967 | 0.78 | QPCT (0.33) | PSMD11PIK3CAMTORQPCTQPCTL | |
| SCHEMBL28178020 | 0.76 | PSMD11 (0.64) | PSMD11PIK3CAMTORQPCTQPCTL | |
| SCHEMBL23227938 | 0.75 | QPCT (0.60) | PSMD11PIK3CAMTORQPCTQPCTL | |
| SCHEMBL29804939 | 0.75 | QPCT (0.60) | PSMD11PIK3CAMTORQPCTQPCTL | |
| SCHEMBL903277 | 0.75 | PRKCI (0.59) | PSMD11QPCTQPCTLPRKCIKDM4E | |
| SCHEMBL8634290 | 0.75 | QPCT (0.68) | PSMD11QPCTQPCTLPRKCIBRD4 | |
| SCHEMBL28360929 | 0.72 | QPCT (0.47) | PSMD11QPCTQPCTLPRKCIBRD4 | |
| SCHEMBL484163 | 0.72 | QPCT (0.60) | PSMD11PIK3CAMTORQPCTQPCTL | |
| SCHEMBL30612370 | 0.72 | QPCT (0.60) | PSMD11PIK3CAMTORQPCTQPCTL | |
| SCHEMBL28361032 | 0.71 | DYRK1A (0.47) | PIK3CAMTORKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | claimed |
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | disclosed |