Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28357181 | 0.78 | PSMD11 (0.48) | QPCTMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28357096 | 0.71 | VRK1 (0.33) | — | |
| SCHEMBL616606 | 0.70 | MAPT (0.41) | QPCTMAPTMEN1ALDH1A1PRNP | |
| SCHEMBL28360907 | 0.69 | LMNA (0.37) | ALDH1A1 | |
| SCHEMBL4453497 | 0.69 | NOTUM (0.32) | — | |
| SCHEMBL9521923 | 0.68 | NOTUM (0.35) | — | |
| SCHEMBL28360982 | 0.66 | ADORA2A (0.38) | — | |
| SCHEMBL28360899 | 0.65 | ADORA2A (0.38) | HTTKMT2ASMN1; SMN2 | |
| SCHEMBL28357412 | 0.65 | ADORA2A (0.32) | MAPTMEN1KMT2A | |
| SCHEMBL5797082 | 0.65 | MAOB (0.35) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | claimed |
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | disclosed |