Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539654 | 0.83 | KDM4E (0.47) | MAOBALDH1A1TSHRKMT2AKDM4E | |
| SCHEMBL5762115 | 0.80 | MAOB (0.49) | MAOBMAOA | |
| SCHEMBL13917260 | 0.80 | ALDH1A1 (0.43) | CYP3A4CYP2D6CYP2C9CYP2C19MAOB | |
| SCHEMBL205724 | 0.78 | KDM4E (0.46) | CYP3A4CYP2D6CYP2C9CYP2C19MAOB | |
| SCHEMBL20588783 | 0.77 | PTGS2 (0.44) | MAPTKMT2AMEN1 | |
| SCHEMBL17321019 | 0.77 | ALDH1A1 (0.41) | CYP3A4CYP2D6CYP2C9CYP2C19MAOB | |
| SCHEMBL14447034 | 0.75 | POLB (0.47) | CYP3A4CYP2D6CYP2C9CYP2C19MAOB | |
| SCHEMBL205244 | 0.75 | POLB (0.53) | CYP3A4ALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL10898831 | 0.73 | MAOB (0.56) | CYP3A4CYP2D6CYP2C9CYP2C19MAOB | |
| SCHEMBL29933496 | 0.73 | MAOB (0.56) | CYP3A4CYP2D6CYP2C9CYP2C19MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111018790-B | Pyridazinone herbicides | FMC公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-111018790-A | Pyridazinone herbicides | FMC公司 | 2020-04-17 | — | — | CN | disclosed |
| CN-106458926-B | Pyridazinone herbicides | FMC公司 | 2020-01-03 | — | — | CN | disclosed |