Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP14 | P50281 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3141855 | 0.84 | KCNH3 (0.63) | CA12CA1MMP2MMP9MMP8 | |
| Hydrochloric Acid SCHEMBL7504066 | 0.82 | KCNH3 (0.66) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL6824926 | 0.80 | CA12 (0.54) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL515914 | 0.80 | CA12 (0.54) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL8373371 | 0.80 | CA12 (0.54) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL515915 | 0.80 | CA12 (0.54) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL6267800 | 0.79 | CA12 (0.63) | CA12CA1MMP2ALDH1A1MEN1 | |
| Water SCHEMBL4754935 | 0.79 | CA12 (0.53) | CA12CA1MMP2MMP9MMP8 | |
| Hydrochloric Acid SCHEMBL4754929 | 0.79 | CA12 (0.53) | CA12CA1MMP2MMP9MMP8 | |
| Water SCHEMBL4754936 | 0.79 | CA12 (0.53) | CA12CA1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746370-B | Preparation method of 4- (4-aminophenyl) morpholine-3-one | 新发药业有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-109384738-B | Preparation method of 4- (4-aminophenyl) morpholine-3-one | 新发药业有限公司 | 2020-10-02 | — | — | CN | disclosed |
| CN-109651286-B | High-selectivity synthesis method of 4- (4-aminophenyl) morpholine-3-one | 新发药业有限公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-110746370-A | Preparation method of 4- (4-aminophenyl) morpholine-3-one | 新发药业有限公司 | 2020-02-04 | — | — | CN | disclosed |