Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | NEK4 | P51957 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 3/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28358885 | 0.87 | CDK4 (0.43) | CDK4CCND1HTR1AMEN1KMT2A | |
| SCHEMBL28358898 | 0.86 | CDK4 (0.41) | CDK4CCND1HTR1AMEN1KMT2A | |
| SCHEMBL28355005 | 0.84 | CDK4 (0.41) | CDK4CCND1HTR1AMEN1KMT2A | |
| SCHEMBL28359180 | 0.83 | HTR1A (0.41) | CDK4CCND1HTR1AHTR2ASSTR4 | |
| SCHEMBL28355198 | 0.82 | CDK4 (0.44) | CDK4CCND1HTR1AMEN1KMT2A | |
| SCHEMBL29108787 | 0.76 | HTR2A (0.43) | HTR1AMEN1KMT2AHTR2ASSTR4 | |
| SCHEMBL28355103 | 0.70 | ALDH1A1 (0.48) | CDK4CCND1HTR1AMEN1KMT2A | |
| SCHEMBL28359128 | 0.69 | ALDH1A1 (0.39) | MEN1KMT2AAKT1MAPT | |
| SCHEMBL734207 | 0.68 | HTR2A (0.52) | HTR1AMEN1KMT2AHTR2ANPC1 | |
| SCHEMBL20542026 | 0.68 | KMT2A (0.47) | HTR1AMEN1KMT2AHTR2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831600-B | Indole AHR inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-110831600-A | Indole AHR inhibitors and uses thereof | 金恩医疗公司 | 2020-02-21 | — | — | CN | disclosed |