Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28358885 | 0.84 | CDK4 (0.43) | HTR1ACDK4CCND1HTR2ASSTR4 | |
| SCHEMBL28358982 | 0.83 | CDK4 (0.42) | HTR1ACDK4CCND1HTR2ASSTR4 | |
| SCHEMBL28358898 | 0.82 | CDK4 (0.41) | HTR1ACDK4CCND1HTR2ASSTR4 | |
| SCHEMBL28355005 | 0.82 | CDK4 (0.41) | HTR1ACDK4CCND1HTR2ASLC6A3 | |
| SCHEMBL28355198 | 0.80 | CDK4 (0.44) | HTR1ACDK4CCND1HTR2ASLC6A3 | |
| SCHEMBL29108787 | 0.72 | HTR2A (0.43) | HTR1AHTR2ASLC6A3SLC6A4SLC6A2 | |
| SCHEMBL21754191 | 0.69 | KMT2A (0.40) | HTR1ACDK4CCND1HTR2ASMN1; SMN2 | |
| SCHEMBL28355103 | 0.68 | ALDH1A1 (0.48) | HTR1ACDK4CCND1HTR2ASSTR4 | |
| SCHEMBL20542026 | 0.66 | KMT2A (0.47) | HTR1AHTR2ASMN1; SMN2 | |
| SCHEMBL20557996 | 0.66 | HTR1A (0.44) | HTR1AHTR2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831600-B | Indole AHR inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-110831600-A | Indole AHR inhibitors and uses thereof | 金恩医疗公司 | 2020-02-21 | — | — | CN | disclosed |