Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 5/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17581885 | 0.79 | MIF (0.41) | CYP3A4MAPTCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL13218978 | 0.75 | ALDH1A1 (0.33) | CYP3A4MAPTCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL13239252 | 0.75 | ALDH1A1 (0.33) | CYP3A4MAPTCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL1099541 | 0.70 | TRPA1 (0.34) | HTTMEN1KMT2A | |
| SCHEMBL31374766 | 0.70 | TRPA1 (0.34) | HTTMEN1KMT2A | |
| SCHEMBL31374767 | 0.70 | TRPA1 (0.34) | HTTMEN1KMT2A | |
| SCHEMBL15058806 | 0.69 | LMNA (0.50) | HTTMEN1KMT2A | |
| SCHEMBL2125917 | 0.69 | LMNA (0.50) | HTTMEN1KMT2A | |
| SCHEMBL3862180 | 0.68 | HPGD (0.45) | HTTMEN1KMT2A | |
| SCHEMBL23969531 | 0.67 | PSMB5 (0.31) | PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642823-A | Pyran derivative and preparation method and application thereof | 青岛秾贝尔生物工程有限公司 | 2020-01-03 | — | — | CN | disclosed |