Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217746 | 0.84 | MAOB (0.44) | PAMMAOBMAOACYP1A2CYP3A4 | |
| SCHEMBL44259 | 0.84 | IDO1 (0.44) | MAOBMAOACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28377983 | 0.76 | PAM (0.57) | PAMAPPCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28840340 | 0.75 | FFAR1 (0.41) | PAMMAOBMAOACYP1A2CYP3A4 | |
| SCHEMBL23138287 | 0.74 | IDO1 (0.38) | MAOBMAOACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2074627 | 0.74 | IDO1 (0.44) | MAOBMAOACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28420190 | 0.72 | TP53 (0.41) | MAOBMAOACYP1A2CYP3A4IDO1 | |
| SCHEMBL28902312 | 0.71 | CYP2D6 (0.44) | MAOBMAOACYP1A2CYP3A4IDO1 | |
| SCHEMBL23088675 | 0.71 | EGFR (0.39) | MAOBMAOACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28632566 | 0.71 | APP (0.61) | PAMAPPCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110656346-A | Method for continuously preparing 2-aryl-3-halogenated-benzothiophene compound by using electrochemical microchannel reaction device | 南京工业大学 | 2020-01-07 | — | — | CN | claimed |
| CN-115044923-B | Method for preparing 2-aryl-3-thiocyano-benzothiophene by utilizing electrochemical reaction | 盐城师范学院 | 2023-05-05 | — | — | CN | disclosed |
| CN-115044923-A | Method for preparing 2-aryl-3-thiocyano-benzothiophene by using electrochemical reaction | 盐城师范学院 | 2022-09-13 | — | — | CN | disclosed |
| CN-110791775-B | Method for continuously preparing 2-aryl-benzothiophene/furan compounds by using electrochemical microchannel reaction device | 南京工业大学 | 2021-02-05 | — | — | CN | disclosed |
| CN-110656346-B | Method for continuously preparing 2-aryl-3-halogenated-benzothiophene compound by using electrochemical microchannel reaction device | 南京工业大学 | 2021-02-02 | — | — | CN | disclosed |
| CN-110483475-B | Method for preparing benzothiophene compound by silver oxide catalysis method | 绍兴文理学院 | 2020-11-27 | — | — | CN | disclosed |
| CN-111675690-A | Benzothiophene compound and preparation and application method thereof | 绍兴文理学院 | 2020-09-18 | — | — | CN | disclosed |
| CN-110791775-A | Method for continuously preparing 2-aryl-benzothiophene/furan compounds by using electrochemical microchannel reaction device | 南京工业大学 | 2020-02-14 | — | — | CN | disclosed |
| CN-110656346-A | Method for continuously preparing 2-aryl-3-halogenated-benzothiophene compound by using electrochemical microchannel reaction device | 南京工业大学 | 2020-01-07 | — | — | CN | disclosed |